Lysine residues in N-terminal tails of histone H3 are the major targets for post-translational modifications (PTMs) such as methylation and acetylation, which are closely associated with gene ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

Prior to the discovery of LSD1, histone methylation was considered a static process. Unlike the dynamic regulation of histone acetylation, through which acetyl groups are deposited by histone ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Japan's epigenetics market is evolving rapidly, with a strong emphasis on AI-driven research and personalized medicine, addressing complex diseases through innovative therapeutic approaches.New Delhi, ...

Histone post-translational modifications (PTMs) mediate the interplay between metabolism and epigenetics, influencing health and disease. Beyond acetylation, short-chain lysine acylations like ...

Examples include DNA methylation and histone acetylation, which can turn genes on or off. Despite their differences, both mechanisms contribute to molecular aging. Researchers have long speculated ...

In a groundbreaking study led by Dr. Ying Chen and her team from Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, researchers have uncovered a novel mechanism behind endothelial ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

Organ transplantation is often heralded as a miraculous medical advancement, offering individuals with failing organs a second chance at life. However, alongside the physical and medical challenges of ...