为解决类风湿关节炎(RA)中滑膜成纤维细胞(FLSs)异常活化导致的关节破坏问题，河南大学人民医院团队揭示了circ_0002970通过调控 ...

The Hippo pathway plays a central role in tissue homoeostasis ... with the Applied Biosystems 7300 with primers targeting CTGF and CYR61: CTGF-Forward: 5′-CCAATGACAACGCCTCCTG-3′, CTGF-Reverse ...

The article, "Dysregulation of PI3K and hippo signaling pathways synergistically induces chronic pancreatitis via Ctgf upregulation" was published in the Journal of Clinical Investigation at DOI ...

Now, researchers at Osaka University have identified the disturbed molecular pathways and revealed the underlying mechanisms that may inform an effective and much-needed therapeutic strategy.

Among these signals, the TGF-β and HIPPO pathways are critical, functioning as tumor suppressors and regulating liver development and regeneration. The review focuses on these pathways' interplay ...

The research examined the Hippo signaling pathway, an evolutionarily conserved signaling pathway that plays a complex role in cellular function as a major pathway promoting fibrosis in systemic ...