LXR may directly interact with HIF-1α. Overall, HIF-1α activation promotes the expression of genes implicated in inflammation (interleukin 1-β), angiogenesis (vascular endothelial growth factor (VEGF) ...
Ubiquitination is a PTM characterized by the covalent binding of ubiquitin (Ub) molecule to a specific target protein. This essential PTM primarily determines protein stability by marking the target ...