Cytochrome c maturation and heme biosynthesis are central processes underpinning cellular respiration and energy conversion. In these pathways, heme – an iron‐containing porphyrin – is ...

† † Vanderbilt Institute of Chemical Biology and ‡ Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States § Department of ...

Their biosynthesis, occurring predominantly in plastids ... In addition, research into heme-dependent cis–trans isomerases has uncovered novel enzymatic controls essential for the isomerisation ...

Heme biosynthesis is a very controlled process that occurs on every nucleated cell types, involving both mitochondrial and cytoplasmatic enzymatic pathways (Shemin 1989). The major part of all heme in ...

As multiple companies vie to expand on Alnylam’s success in commercializing RNAi therapeutics, the pioneering company has set ...

Disc Medicine, Inc. (NASDAQ:IRON), a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel treatments for patients suffering from serious ...

(22) Little is known about RufO’s catalysis, including the substrate recognition mechanism, the changes at the catalytic site and overall protein structure in response to peptide binding, the ...

Positive updates across all programs, including longer term efficacy and safety data from the HELIOS open-label extension trial of bitopertin in erythropoietic protoporphyria (EPP), additional ...

Award-winning research presented by Hangjie Fu at EHA shows that ellagic acid can protect against iron overload-induced liver ...

There are also two types of dietary iron: heme and nonheme. Heme iron is found in meat, poultry, and seafood. Nonheme iron is mostly found in plants. Heme iron is more bioavailable than nonheme ...

Blood is the life-maintaining fluid that flows through the body's blood vessels: Red blood cells (erythrocytes). These carry oxygen from the lungs to the rest of the body. White blood cells ...