Herpes simplex virus-1 (HSV-1) is a pathogen that may cause severe encephalitis in humans. In this study, we aimed to investigate the role of interleukin-4 (IL-4) in a model of HSV-1 brain infection.

When mice received this AAV-UGI vector before exposure to HSV-1, they were far more likely to survive. However, when the mice lacking APOBEC1 received this treatment, the protective effect vanished, ...

When mice received this AAV-UGI vector before exposure to HSV-1, they were far more likely to survive. However, when the mice lacking APOBEC1 received this treatment, the protective effect ...

When mice received this AAV-UGI vector before exposure to HSV-1, they were far more likely to survive. However, when the mice lacking APOBEC1 received this treatment, the protective effect ...

Patients with HSV-1 who used antiherpetics were less likely to develop Alzheimer disease than those who did not. HealthDay News — Herpes simplex virus type 1 (HSV-1) is associated with an ...

TSP-1 reduced C3 and C5 cleavage and formation of the membrane attack complex, attenuating complement-mediated injury in AAV models. Complement activation is a relevant driver in the ...

† Department of Chemistry, Kanabar Laboratory for Nanomaterials, Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat Gan 5290002, Israel ‡ The Mina and Everard Goodman ...

Adults aged 50 years and older with a history of herpes simplex virus type 1 diagnosis were up to 1.8 times more likely to have Alzheimer disease, although the risk was lowered by use of antiherpetics ...

A new study has found the herpes simplex virus type 1 (HSV-1), which causes cold sores, may be linked to the development of Alzheimer's disease. This idea is not entirely new. Previous research has ...

Joyce Siette receives funding from the National Health and Medical Research Council on a Targeted Call for Research on cultural, ethnic and linguistic diversity in dementia research. A new study ...

and the University of Washington’s Department of Medicine (UW Medicine) has added to the mounting evidence, finding an association between herpes simplex virus type 1 (HSV-1) and the risk of ...

Summary: A large study suggests that symptomatic infection with herpes simplex virus 1 (HSV-1)—best known for causing cold sores—may significantly raise the risk of developing Alzheimer’s disease.