Forty boxes recently arrived at a mostly empty lab space in University City where the Wistar Institute opened this month a ...

Bengaluru: Eliminating AIDS is a Sisyphian challenge. Treatments mostly miss the Human Immunodeficiency Virus (HIV) that are ...

Without CD4 T helper cells, the immune system cannot recognize and coordinate a defensive response to diseases like HIV. This is when a person is said to be immunocompromised. During maturation, ...

A mouse study at Memorial Sloan Kettering Cancer Center has found that adding Nef, a protein from HIV, allows donor CAR T cells to avoid detection by the immune system while still attacking tumors. A ...

The authors of this study hypothesized that using engineered CAR T cells to recognize and attack PD-1+ cells might be effective at depleting this HIV reservoir. Previously, the Corey lab tested ...

Specifically focused on a kind of immune response mediated by CD8 + T cells, the research resolved an open question in HIV research: Do these T cells control HIV by killing HIV cells or by ...

However, HIV may still exist in cells that are in a resting (latent) state, creating an HIV reservoir. CD4 T cells, a type of white blood cell, are the most well-studied HIV reservoir. Identifying ...

You may like HIV/AIDS: Facts about the viral infection that attacks the immune system ... However, stem cell transplants wouldn't be appropriate for patients who are HIV-positive but don't have ...

HIV targets CD4+ T cells ... involvement in attacking and neutralizing pathogens. In contrast, CD8+ T cells directly attack pathogens and cancerous cells by binding to them and secreting toxic ...

T-cell immunotherapy has great promise. HIV is hard to treat because it attacks CD4 T cells, paralyzing the patient’s immune system. So treating HIV is also related to T cells, even though these ...

CAR T-cell therapy involves the removal of a patient’s immune system’s T-cells and genetically modifying them to recognize and attack HIV-afflicted cells in the host. Dr. Mehrdad Abedi, a professor of ...