The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

There was a history of gout for many years. Tophi were present on the joints of both hands and the left great toe. The urine had a specific gravity of 1.014 and gave a ++ test for albumin.

Other symptoms can include: Decreased range of motion Redness Swelling in finger joints Warm or hot skin around the affected ...

Gout can affect other joints. It may also cause “tophi” to develop (hard swellings around joints and the ears). Gout typically occurs in bouts or attacks, before settling with treatment and ...

Gout is a disease characterized by recurrent attacks of arthritis, in which uric acid appears in excessive amounts in the blood and may be deposited in joints, tendons and other tissues.

Recurring gout is often due to the deposition of urate crystals in bumps or nodules called tophi which generally are not painful but during flares of gout can become extremely painful. Those with ...

Arthrosi Therapeutics, Inc., a late-stage biotechnology company developing a potentially best-in-class, highly potent and selective next generation URAT1 inhibitor to reduce serum urate (sUA) levels, ...

However, given the likely contribution of higher comorbidities to poorer health outcomes among respondents, comorbid status may be confounded with gout flares and tophi in the analyses.

Gout can affect other joints. It may also cause “tophi” to develop (hard swellings around joints and the ears). Gout typically occurs in bouts or attacks, before settling with treatment and becoming ...