近日，一篇发表在国际杂志Frontiers of Medicine上题为“ING5 inhibits aerobic glycolysis of lung cancer ... 了ING5的过表达会显著增加PDK1 Y163位点的磷酸化，进而 ...

This led to a decrease in PDHA1 S293 phosphorylation and an increase in PDH enzyme activity, promoting oxidative phosphorylation and reducing glycolysis. The clinical relevance of PDK1 Y163 ...

Conclusions c-Fos modulates cellular bioenergetics in chondrocytes by balancing pyruvate flux between anaerobic glycolysis and the tricarboxylic acid cycle in response to OA signals. We identify a ...