While chondroitin sulfate and glucosamine sulfate both have well-documented, beneficial effects in patients with osteoarthritis, the exact molecular actions of these drugs are also unknown.

U.S. consumers spent $753 million in 2012 on supplements of glucosamine and chondroitin in an attempt to relieve pain and stiffness from arthritis, according to the Nutrition Business Journal.

Patented crystalline glucosamine sulfate (pCGS) is a type of glucosamine ... It's commonly combined with chondroitin and other compounds in supplements marketed to support bone and joint health.

Each 8-ounce serving has 1,500 milligrams of glucosamine hydrochloride and 200 milligrams of chondroitin sulfate, along with green-tea extract and vitamins C and D. Orthopedic surgeon Kevin Stone ...

Glucosamine is a key element in the framework ... with osteoarthritis and joint wear and tear due to old age or injury. Chondroitin is a component of cartilage that helps it to attract and retain ...