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Glucocorticoid steroids improved muscle performance through distinct, ... myofibers from male mice showed an increased expression of genes in the IGF1/PI3K pathway, which promoted muscle growth, ...
Researchers have uncovered pathways involved in the body's response to glucocorticoid treatments and identified a novel biomarker that could be used to monitor how these drugs work in patients.
Non-glucocorticoid therapies can decrease risk for complications from lifelong glucocorticoid treatment. Yes, I do think we need non-glucocorticoid forms of therapy to treat 21-hydroxylase ...
Glucocorticoids regulate vital biological processes by affecting gene encoding through a DNA-binding ... be influenced in drug-resistant prostate cancer through an alternative pathway.
By Pooja Toshniwal Paharia New research uncovers gut microbiome links to lupus and IBD, pointing to potential biomarkers and ...
ABBV-154, an antibody-drug conjugate comprising adalimumab conjugated to a proprietary glucocorticoid receptor modulator, shows potential for extending flare-free periods in patients with ...
Epidural glucocorticoid injection is an intervention commonly used for managing lumbosacral radicular pain. The goal of the injection is to administer glucocorticoids to the epidural space to ...
Glucocorticoid therapy began a median 4 months after thyroid eye disease diagnosis. The mean clinical activity score at baseline was 4.4 of a maximum 7 points, with 73% of participants having a ...
In this trial involving patients with giant-cell arteritis, upadacitinib at a dose of 15 mg with a 26-week glucocorticoid taper showed efficacy superior to that of placebo with a 52-week ...
In the PULSE-MI trial, prehospital pulse-dose glucocorticoid treatment in STEMI patients did not reduce the final infarct size at 3 months, despite improvements in acute outcomes.