also named Globoid Cell Leukodystrophy (GLD). This severe leukodystrophy, caused by galactosylceramidase (GALC) mutations, primarily affects infants and young children, causing symptoms such as ...

There is currently no cure for SLE, but the Nature Medicine paper sparked hope that one might be near. The study tested a relatively new technology called CAR T cell therapy, which often uses a ...

It is rapidly progressive and fatal. Also known as globoid cell leukodystrophy, Krabbe disease is classified as a leukodystrophy and a lysosomal storage disorder (LSD). LSDs occur when a cell’s ...

Krabbe disease (KD), also known as globoid cell leukodystrophy, is a rare autosomal recessive condition caused by mutations in the galactocerebrosidase (GALC) gene. KD is more common in infants and ...

1 Department of Neurology, Lanzhou University Second Hospital, Lanzhou, China 2 Department of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, China Globoid cell leukodystrophy (GLD), ...

In one out of 100,000 infants, a mutation in the GALC gene causes an incurable, always fatal disorder known as infantile Krabbe disease, or globoid cell leukodystrophy. Most children with the ...