After 5-10 generations of inbreeding, mouse colonies should be “refreshed”, to remove or prevent genetic drift accumulation in the colony. Several methods to refresh the genetic background may ...

How genetic drift arises and its prevalence in mouse ... The best way to determine whether genetic background matters is to perform controlled, side-by-side experiments and compare.

The founder effect is an extreme example of "genetic drift." Genes occurring at a certain frequency in the larger population will occur at a different frequency -- more or less often -- in a ...

Called genetic drift, this type of variation is a random, statistical fluctuation in the frequency of a gene as it appears in a population from one generation to the next. My colleagues and I have ...

Populations evolve in two primary ways: genetic drift and natural selection. Genetic drift refers to random fluctuations in the frequencies of certain genes between generations in populations.

Much change is due to random genetic drift rather than positive selection. It could be called the survival of the luckiest. You might think that largely neutral mutations would remain restricted ...

In new work published in PNAS, University of Minnesota Medical School researchers found that genetic background and social rank are critical contextual modifiers of aging and lifespan in animal ...