Understanding human biology requires more than mapping our genes—we must also understand how gene expression is regulated to ...

Mosaic brains and the seesaw effect in dysregulated genes Gene regulation is the process of turning genes on and off.

Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin organization and cell cycle state, including quiescence. Gene expression is important because a specific ...

Gene regulation relies on the specificity of transcription factor (TF)–DNA interactions. Limited specificity may lead to crosstalk: a regulatory state in which a gene is either incorrectly ...

Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

By mapping all the different elements, the platform shows how gene regulation works in the brain and how it could be affected by mutations or disorders. This project’s broad aim is to help ...

“The problem is that those agents aren’t specific. You end up getting gene regulation in all cells, not just the cancer cells you intended to target for gene regulation.” That’s where the precision of ...

Scientists have discovered that coordination between basic cellular processes is lost with increasing age. Gene regulation in our cells -- the decision when which proteins are produced for the ...

Image: Adobe Stock The pair’s discovery “revealed a completely new principle of gene regulation that turned out to be essential for multicellular organisms, including humans,” according to a ...

Our research program focuses on two primary points of control: transcription of messenger RNA (mRNA) and post-transcriptional regulation of mRNAs by microRNAs (miRNAs). A critical control point for ...

On issues surrounding gene editing in the food supply, this difference in regulation “is causing trade disruption on the plant side and will clearly cause disruption on the animal side,” he says.

Imprinting is yet another process involved in eukaryotic gene regulation; this process involves the silencing of one of the two alleles of a gene for a cell's entire life span. Imprinting affects ...