资讯

搜狐3 年
GAPDH，Tubulin，Actin选哪个做WB内参更好？
感谢您的关注！ GAPDH,Tubulin,Actin是WB实验中最常用的三种上样内参（loading control），因被认为表达水平受环境因素影响较小，在个体各个生长阶段的大多数或几乎全部组织中持续表达或变化很小，所以被称为管家基因（ house-keeping genes ），是WB实验中校正上样量 ...
搜狐3 年
GAPDH，Tubulin，Actin选哪个做WB内参更好？
为了避免类似情况，请为“科研人直通车”设置星标，文章点一下“在看”，保持互动热度，就能及时收到每期推送啦！ GAPDH,Tubulin,Actin是WB实验中最常用的三种上样内参（loading control），因被认为表达水平受环境因素影响较小，在个体各个生长阶段的大多数或 ...
Frontiers3 年
GAPDH, Interferon γ, and Nitric Oxide: Inhibitors of Coronaviruses
One possible (and perhaps unlikely) therapeutic target could be GAPDH (glyceraldehyde-3-phosphate dehydrogenase). Studies have show that downregulation of GAPDH leads to a decrease in interferon gamma ...
PNAS9 年
Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade
Autophagic actions of cocaine are mediated by the nitric oxide-glyceraldehyde-3-phosphate dehydrogenase signaling pathway. Thus, cocaine-associated autophagy is abolished by depleting GAPDH via shRNA; ...
eLife10 年
Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a ...
We identified and confirmed a novel mode of regulation specific to aerobic glycolysis where flux through GAPDH, the enzyme separating lower and upper glycolysis, is the rate-limiting step in the ...
Frontiers11 年
Plant cytoplasmic GAPDH: redox post-translational modifications and moonlighting properties
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a ubiquitous enzyme involved in glycolysis and shown, particularly in animal cells, to play additional roles in several unrelated non-metabolic ...
Nature18 年
GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Here, we report that the protein accumulates ...