Recent work revealed new insights into the temporal regulation of G1–S cell cycle transcription, during proliferation and in response to activation of the DNA replication checkpoint. This has ...

Sp1 binding sites have been identified in enhancer/promoter regions of several growth and cell cycle regulated genes, and it has been shown that Sp1 is increasingly phosphorylated in G1 phase of ...

The cell cycle contains 4 stages; Gap 1 (G1) phase, synthesis (S) phase, gap 2 (G2) phase and mitosis (M) phase. For most human cells, a single cell cycle takes approximately 24 hours.

To understand the dynamics of cell-cycle status in tumors, Florian’s team used two new reporters: one to visualize G1 and the other to see G2, S, and M phases. “Because [FUCCI4] uses fluorescent ...

Conclusions: Most patients with G1-S phase cell-cycle alterations harbored co-genomic alterations. Our current study suggests that targeting co-alterations along with cell cycle molecular alterations ...

The cell cycle is a complex process that involves the growth and division of a cell. It is divided into four phases: G1, S, G2, and M. During each phase, the cell undergoes a series of events that ...

The cell cycle is regulated by cyclins, ... Phosphorylation by CDK-2-cyclin E complex prevents this inhibition and so progression from G1 to S phase can continue. Overall, ...

Since 1974, scientists have thought that cells make the decision to replicate or quiesce only in a short window during the phase of the cell cycle called G1, as if cells make their go/no-go ...

The cell cycle is the process in which a growing cell duplicates all of its DNA, copying each base precisely once, and then divides into two daughter cells. It consists of four phases: S, for ...

The classic view of the cell cycle was established by pioneering experiments in yeast and sea urchins by Hartwell, Nurse, Hunt, and others. 3 In principle, the cell cycle represents the molecular ...

image: AIEgen-based fluorescence detecting system for analysis of TERT mRNA and telomerase activity in different phases of cell cycle (G0/G1, G1/S, S and G2/M phase). view more .

It's only present in the G1 phase. The green marker detects a protein called geminin, which is present in the S, G2, and M phases. So, these two fluorescent markers can tell you only if a cell is ...