Phosphorylation by CDK-2-cyclin E complex prevents this inhibition and so progression from G1 to S phase can continue. Overall, cyclins are responsible for the progression of the cell cycle ...

This cascade culminated in G0/G1 phase cell cycle arrest. Furthermore, analysis of TCGA-HCC datasets confirmed inverse correlations between PPP1R12B and PAK2 or CTNNB1 (β-catenin) expression.

DelveInsight's, “Bladder Cancer Pipeline Insight 2025” report provides comprehensive insights about 80+ companies and 100+ ...

A new study suggests that emotions such as anger, irritability, and feeling out of control may be more pronounced based on a woman's menstrual cycle phase and her reproductive age. Results of the ...

Neoadjuvant nivolumab (Opdivo) plus chemotherapy significantly improved overall survival (OS) compared with chemotherapy alone for patients with resectable non-small cell lung cancer (NSCLC), the ...

Perelman School of Medicine have developed a dual-target CAR-T cell therapy that has slowed GBM tumor growth in nearly two-thirds of patients based on results from a Phase I clinical trial.

Perturbational single-cell RNA sequencing of patient tumors in Merkel cell and small cell lung carcinomas.

which focus on early-phase and hybrid-hotel manufacturing — Made Scientific delivers a full continuum of services designed to meet the evolving needs of cell therapy developers progressing T ...

Molecular landscape of distinct follicular lymphoma histologic grades: Insights from genomic and transcriptome analyses.