The accurate transition from G1 phase of the cell cycle to S phase is crucial for the control of eukaryotic cell proliferation, and its misregulation promotes oncogenesis. During G1 phase ...

Sp1 binding sites have been identified in enhancer/promoter regions of several growth and cell cycle regulated genes, and it has been shown that Sp1 is increasingly phosphorylated in G1 phase of ...

The cell cycle contains 4 stages; Gap 1 (G1) phase, synthesis (S) phase, gap 2 (G2) phase and mitosis (M) phase. For most human cells, a single cell cycle takes approximately 24 hours. However ...

Increased tumor purity and improved biomarker detection using precision needle punch enrichment of pathology specimen paraffin blocks: Method validation and implementation in a prospective clinical ...

Claudia Waskow at the Carl Gustav Carus Faculty of Medicine at Dresden Technical University is now describing a new mechanism in which the length of the G1 phase of the cell cycle has a dramatic ...

A new method can capture detailed information about all four phases of the cell cycle in real time using fluorescent proteins. Michael Lin was always curious about cell biology, but he became ...

The cell cycle consists of four phases (G1, S, G2 and M), all of which are characterized by different factors. The S phase is characterized by DNA synthesis, and in the 1960s it was discovered ...

The cell cycle is a complex process that involves the growth and division of a cell. It is divided into four phases: G1, S, G2, and M. During each phase, the cell undergoes a series of events that ...

G1 before S phase and G2 between S and M. The cell cycle is tightly regulated; ensuring that cells proceed through it at the proper pace and at the proper time is essential to maintaining an ...

Since 1974, scientists have thought that cells make the decision to replicate or quiesce only in a short window during the phase of the cell cycle called G1, as if cells make their go/no-go ...

Upon progression through the cell cycle, the PyTPA-DNA faintly fluoresced in G0/G1 stage but demonstrated an enhancement of fluorescence when responded to G1/S phase, finally reached the strongest ...

Cyclin D and CDK4/6 play a key role in cell-cycle progression by phosphorylating and inactivating the retinoblastoma protein, a tumor suppressor that restrains G1- to S-phase progression. The ...