As time goes by, our bodies change, you know, even the brain. A major change is how brain structure seems to shrink with age. Studies show that this happens at both large and small levels inside. You ...

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Furthermore, we demonstrated that the enzyme DHFR2, a poorly characterized paralog of the folate pathway regulator DHFR, plays a key role in regulating mitochondrial homeostasis. Using organoid models ...

Introduction. Folate is essential for normal DNA and RNA biosynthesis and it is required for homocysteine metabolism. It appears obvious that folate is essential for normal fetal development, and ...

Folate is a vitamin cofactor required as a one-carbon (1C) donor in multiple metabolic pathways. Its role is within the folate-mediated one-carbon metabolism (FOCM).

B vitamins serve a range of important functions in the body: They help you form new blood cells and maintain cellular health, promote metabolism (the conversion of food into energy), and contribute to ...

The Folate Factor Among the busiest of B vitamins, folate has a special role in depression treatment. By Hara Estroff Marano published January 2, 2019 - last reviewed on March 4, 2019 ...

Homocysteine was an important intermediate product in the one-carbon metabolic (OCM) pathway and other participants in this pathway could influence the circulating concentration of homocysteine (7, 8) ...