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The key lies in extracting the relationship between the signals inside the cells (intracellular signals) and those recorded on their surface (extracellular signals). "We discovered that ...

Thyroid Peroxidase (TPO) is a 110 kD membrane bound hemo-glycoprotein with a large extracellular domain, and a short transmembrane and intracellular ... human TPO as the antigen, should replace ...

Autophagy, a cytosolic structure degradation pathway is involved in the maintenance of cellular homeostasis, degradation of intracellular pathogens and generation of energy ... a biomarker of COVID-19 ...

Chloroquine and hydroxychloroquine impede lysosomal activity and autophagy, leading to a decrease of antigen processing and presentation ... Autophagy is a countermeasure to infectious diseases ...

"We were working on Spirulina on a totally different project, but when we realized that nobody has previously worked on extracellular ... with this vaccine antigen and we realized that compared ...

Cellular immunity is most effective against cells infected with viruses, intracellular bacteria ... immune surveillance via upregulation of antigen-processing and presentation components.

1Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut. 2Department of Genetics, Yale University School of Medicine, New Haven, Connecticut.