The gastrointestinal wall is a significant site of first-pass metabolism for oral drugs, which is commonly associated with CYP450 and UGT enzymes. However, contributions of esterase activities in the ...

2a). Figure 2: Mutations in the esterase PfPARE are responsible for resistance to pepstatin esters. We performed in-cell metabolism experiments to determine the fate of pepstatin and its ester ...

Use of a leukocyte esterase strip test may be a reliable tool to diagnose persistence of infection during second-stage revision procedures for periprosthetic joint infection, according to results.

‘The FDA approval of a C1-esterase inhibitor (human) to prevent attacks of hereditary angioedema can prevent the appearance of life-threatening swellings in patients with the genetic disorder.

The gastrointestinal wall is a significant site of first-pass metabolism for oral drugs, which is commonly associated with CYP450 and UGT enzymes. However, contributions of esterase activities in the ...