Activating agents enable the efficient preparation of organozinc complexes from zinc metal and organohalides, but their mechanisms had been obscured by the heterogeneous nature of these systems.

Alpha-enolase (ENO1) is considered as a pivotal autoantigen in early RA ... through the CD14-dependent TLR4 pathway and contribute to elucidate the role of this autoantigenin the RA pathophysiological ...

From Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville Campus, Victoria, Australia (R.H.R.) Division of Endocrinology and Metabolism (E.D.A.), ...

A joint research group team led by Sayuri Tsukahara and Tetsuji Kakutani of the University of Tokyo has clarified a mechanism of how retrotransposons, genetic elements that can "jump around ...

Laboratory of Chemical Biology, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven 5600 MB, The Netherlands ...

To further explore the consequence of citrullination on the inhibitory effect of C1-INH in the contact system and more importantly in the complement system, we studied the mechanism of how ...

Unraveling these mechanisms would offer therapeutic options to ameliorate or perhaps even cure disorders that are now leading causes of mortality. In this millenium, we will be required to answer ...