It is characterized by the accumulation of cholesteryl esters, macrophages, and fibrous elements in the intimal region underlying the endothelial-cell monolayer.

In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal ...

These endothelial abnormalities facilitated the accumulation and infiltration of monocytes and macrophages into the intima, where the macrophages exhibited both inflammatory and anti-inflammatory ...

Hongu, T., Pein, M., Insua-Rodríguez, J. et al. Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs.

A specific subset of TAMs that produce a protein called Tie2 can also stimulate angiogenesis through secretion of vascular endothelial growth factor (VEGF) and other molecules (2). At the same time, ...

More information: Xingsheng Ren et al, Macrophage-endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa, Journal of Clinical Investigation (2023). DOI: 10.1172/JCI170733 ...

The newly identified progenitor cell, discovered in the outer layer of the aorta of adult mice, differentiates into endothelial cells and macrophages. The researchers thus dubbed it an ‘EndoMac ...

Hongu, T., et al. (2022) Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs. Nature Cancer. doi ...

These endothelial abnormalities facilitated the accumulation and infiltration of monocytes and macrophages into the intima, where the macrophages exhibited both inflammatory and anti-inflammatory ...