It is characterized by the accumulation of cholesteryl esters, macrophages, and fibrous elements in the intimal region underlying the endothelial-cell monolayer. The rupture of such lesions can ...

The enzyme arginase-II has an important role in cardiac aging, and blocking it could help hearts stay young longer.

Effect of ligand binding domain activating mutations of ESR1 on cellular metabolism, liver tropism, and chemotherapy resistance. This is an ASCO Meeting Abstract from the 2019 ASCO Annual Meeting I.

Experimental and clinical studies suggest that there is an evolving role for endothelial progenitor cells in neoangiogenesis and rejuvenation of the endothelial monolayer. 6,12,17 The presence of ...

Hongu, T., Pein, M., Insua-Rodríguez, J. et al. Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs.

More information: Xingsheng Ren et al, Macrophage-endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa, Journal of Clinical Investigation (2023). DOI: 10.1172/JCI170733 ...

These endothelial abnormalities facilitated the accumulation and infiltration of monocytes and macrophages into the intima, where the macrophages exhibited both inflammatory and anti-inflammatory ...

A specific subset of TAMs that produce a protein called Tie2 can also stimulate angiogenesis through secretion of vascular endothelial growth factor (VEGF) and other molecules (2). At the same time, ...

These endothelial abnormalities facilitated the accumulation and infiltration of monocytes and macrophages into the intima, where the macrophages exhibited both inflammatory and anti-inflammatory ...