Figure 1: The Nur77–GFP BAC transgenic reporter is responsive to antigen-receptor signalling in vitro. The reporter responded to TCR-dependent signalling in vivo, as shown by GFP expression at ...

In the endogenous pathway, MHC class I molecules present endogenous antigens derived from pathogen-specific proteins produced within infected cells. However, in the exogenous pathway, MHC class II ...

Certain peptides are preferentially loaded onto MHC I, further processed for immune surveillance (antigen processing) and presented on the cell surface. Peptides that come from normal endogenous ...

Figure 5: Endogenous nanomineral is co-localized with luminal peptidoglycan and dietary antigen in Peyer's patch APC. Collectively, these findings point to a role for endogenous gut nanomineral ...

These antigens are typically recognized by the immune system as non-self and trigger an immune response to eliminate the invading organism. Endogenous antigens are substances that originate within the ...

Chimeric antigen receptor (CAR) ... where they in turn orchestrate the activation of endogenous cytolytic T cells. 1 In a proof-of-concept study published in 2022, ...

SQZ AACs are a novel cellular immunotherapy candidate designed to transport tumor-specific antigen and TLR agonists to the patient’s endogenous, professional, antigen presenting cells in vivo.

At enrollment, 50% of participants were seropositive for endogenous neutralizing antibodies and 59% had anti-nucleocapsid antibodies. Also, 95% of participants had plasma antigen levels of 3 ng/L ...

An antigen-presenting cell (APC) takes up the proteins and delivers them to a compartment inside itself called the endosome, where the proteins are digested ("processed") into peptides.