In line with the role of autophagy as a major degradation system for MHC-II loading and antigen presentation, we observe ...

A team of physicians from Bochum are the first to successfully use CAR T-cell therapy to treat two patients with a rare ...

An antigen is a molecule that may be recognized by the immune system and trigger an immune response by activating leukocytes (white blood cells) that fight disease. Antigens may be present on invaders ...

Tumors are often infiltrated by T lymphocytes recognizing either self- or mutated antigens but are generally inactive ... This resulted in effective tumor growth inhibition or elimination in two ...

In the endogenous pathway, MHC class I molecules present endogenous antigens derived from pathogen-specific proteins produced within infected cells. However, in the exogenous pathway, MHC class II ...

But on Friday, the Food and Drug Administration authorized use of the first antigen test -- a potentially cheaper and faster way to detect people who have the virus. PCR-based tests look for the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Active ...

Repurposing endogenous immune pathways to improve chimeric antigen receptor T-cells potency [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14 ...

To defend an organism against invaders such as viruses and bacteria, cells of the immune system need to recognize and respond to foreign microbes. However, these immune cells must also avoid attacking ...