This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

Further cell divisions lead to the formation of the primitive endoderm, which forms a blastocyst. This structure implants around one week after fertilization. As development continues, the epiblast ...

Here, using gastruloids –3D aggregates of mouse embryonic stem cells- we study the formation of one of the three germ layers, the endoderm. We show that the endoderm is generated from an epiblast-like ...

The word hamartoma (from the Greek Hamartia - error, Oma - tumoral growth) (ZARBO & CLATCHEY, 1983) was established in 1904 by Eugem Albrecht to characterize tumors with abnormal growth of a set of ...

The pectoral fins of ancestral fishes had multiple proximal elements connected to their pectoral girdles. During the fin-to-limb transition, anterior proximal elements were lost and only the most ...