Endosomes are membrane-bound cytosolic vesicles with three major compartments namely early, late, and recycling endosomal compartments. Endosomes are the integral parts of the endocytic process ...

In this talk we will show how STELLARIS provides an integral access to these different layers of information from dynamic, structural, and mechanistic insights into vesicle trafficking. The endocytic ...

Importantly, this compartment contained Tlg2p, which is a target protein for endocytic vesicle. Notably, both substances and proteins destined for degradation by lysosomes and recycling by the ...

To analyze the data further, the researchers grouped endocytic events based on the clathrin lifetimes and the models of vesicle formation. This revealed interesting features. “We found that ...

At a critical moment the cell membrane buckles and invaginates into the condensate, ultimately being pinched off to form a spherical vesicle. How membrane buckling occurs has been a mystery, but the ...