This is a valuable and rigorous study that addresses the question of what determines the spatial organization of endocytic zones at synapses. The authors use compelling approaches, in both Drosophila ...

The corresponding polymersomes exhibited a morphology transition from vesicles at neutral pH values to micelles upon lowering the pH value down to endosomal pH value as investigated by DLS and ...

Giant membrane vesicles (GUVs) and giant plasma membrane vesicles (GPMVs) are valuable models for studying the properties of cellular membranes. We analyzed experimental data on vesicle shapes in ...

The mechanisms of vesicle recycling at high stimulation frequency. In their publication, the researchers shed new light on the vesicle recycling process in hippocampal synapses. With their model, they ...

BACKGROUND: Preeclampsia is a challenging pregnancy disorder to treat, and current preventive measures are not always effective. Aspirin is prescribed as a preventive agent for pregnant women who are ...

BACKGROUND: Carotid atherosclerosis is orchestrated by cell-cell communication that drives progression along a clinical continuum (asymptomatic to symptomatic). Extracellular vesicles (EVs) are ...

The endolysosomal system plays a critical role in controlling proteome abundance and quality in eukaryotic cells. First, specific plasma membrane (PM) proteins—referred to here as cargo—undergo the ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles ...

How do we think, feel, remember, or move? It all depends on transmission of chemical signals in the brain, carried and released by molecular containers called vesicles. In a new study, researchers ...

Since the new vesicles were formed from the retentate vesicles and not from the filtrate, i.e. the amphiphiles left in the bulk, these observations confirm that formation of “newer” vesicles can be ...