ER aminopeptidase 1 (ERAP1) is an intracellular enzyme that generates antigenic peptides and is an emerging target for cancer immunotherapy and the control of autoimmunity. ERAP1 inhibitors described ...

Dysfunction of the autophagy–lysosome pathway has been implicated in a variety of neurodegenerative diseases, including Alzheimer’s disease, highlighting the value of new strategies for therapeutic ...