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Methods: 50 patients with CHF (left ventricular ejection fraction (LVEF) < 40%) were randomly assigned to valsartan (80 mg/day; n = 25) or enalapril (5 mg/day; n = 25). All patients were also treated ...

Mechanistically, phosphorylated Smad1/5/9 act as pivotal mediators of the anti-aging properties of enalapril ... The mice had ad libitum access to food and water. A daily dosage of 30 mg/kg of ...

Abstract We studied six healthy male subjects in a randomized, placebo-controlled, single-blind fashion to determine the comparative effects on renal hemodynamics and natriuresis of the ...

Figure 2. Dot plot of serum creatinine (A,B), symmetric dimethylarginine [SDMA; (C,D)], and urea nitrogen (E,F), concentrations in 29 dogs with proteinuric chronic kidney disease (CKD) before (day 0), ...

How does enalapril work (mechanism of action)? Enalapril blocks the angiotensin-converting enzyme (ACE) from forming a hormone called angiotensin II. When angiotensin II binds to receptors ...

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