A strategic atom swap solves a longstanding selectivity problem in the synthesis of complex pyrazoles and is something that ...

Indeed, hydroxymethylacylfulvene (HMAF) has been evaluated for treating various cancers by selectively targeting tumor cells through DNA alkylation. However, the electrophilic intermediates formed ...

Department of Chemistry and Intelligent Computing for Sustainable Development Research Center, National Taiwan Normal University, Taipei 11677, Taiwan, R.O.C ...

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd. 38, Beijing 100191, China ...

Glutathione peroxidase 4 (GPX4) is one of the most important antioxidant enzymes. As the key regulator of ferroptosis, GPX4 has attracted considerable attention in the fields of cancer, cardiovascular ...