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Classical EMT, as first described in embryonic development, results in the transition of epithelial (E) cells to cells with a mesenchymal (M) phenotype, defined by prototypical markers ...
Researchers have provided a comprehensive profile of multiple epithelial-mesenchymal transition (EMT) markers and to demonstrate that Snail and Twist, but not Slug, are the major inducers of EMT ...
A) Schematic outlining the process of FMT and EMT assays. B) Representative images showing the segmental analysis masks used for quantification of markers. Examples shown: α-smooth muscle actin ...
Acquisition of mesenchymal markers during the epithelial–mesenchymal transition process may explain why certain CTCs are missed during epithelial marker-based assays. An ideal CTC detection ...
CD63 helps to reduce the migration and invasion of melanoma cells by inhibiting markers associated with EMT. CD63 interacts with a range of signaling molecules and receptors, influencing various ...
As cells undergoing the epithelial-mesenchymal transition move from left to right through the EMT chip, those expressing mesenchymal markers (red) break away and move independently from other ...
making such EMT populations good candidates for tumor initiation in PDAC. Receptor tyrosine kinases (RTKs) are a class of cell surface markers whose aberrant activation causes cancer progression. In ...
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