此前研究提出，DOPA 脱羧酶（DOPA decarboxylase，DDC，也叫芳香族 L - 氨基酸脱羧酶 Aromatic - L - amino acid decarboxylase，AADC）可能是 LBDs 有前景的脑脊液（cerebrospinal fluid，CSF）生物标志物，不过血浆 DDC 水平的研究结果却不一致，这使得血浆 DDC 作为 LBDs 潜在生物标志物 ...

Dopa decarboxylase, an enzyme involved in the synthesis of the neurotransmitter dopamine, catalyses the formation of functional dopamine through decarboxylation of a precursor tyrosine derivative.

In participants who had Parkinson’s disease or DLB, the cerebrospinal fluid had much higher levels of DOPA decarboxylase – an enzyme that helps with the production of dopamine – compared ...

Anil Modak, PhD, of Cambridge Isotopes Laboratories, in Andover, Massachusetts, reported early feasibility data using the test, which uses measures of dopa decarboxylase enzyme activity in PD ...

It is designed to deliver a functioning human dopa decarboxylase (DDC) gene directly into the putamen, thereby increasing the AADC enzyme and restoring dopamine production. The BLA is supported by ...