Scientists at Novo Nordisk in Denmark have applied flow chemistry to enhance the cleavage of oligonucleotides. Utilising Vapourtec’s R-Series flow chemistry system to undertake their research, the ...

Cancer researchers at Children's Medical Research Institute have discovered an "unexpected mechanism" that our cells use to ...

Mitosis is the complex process in which duplicated chromosomes are condensed, segregated with the help of the mitotic spindle, and packaged in to daughter cell nuclei. Mitosis occurs in five ...

Although natural sources of compounds that contain the oxazolidin-2-one nucleus are very rare, 5 Kakeya et al. 6 were able to isolate a novel compound belonging to this class, ...

Department of Pure and Applied Chemistry, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan ...

New York, USA, Feb. 25, 2025 (GLOBE NEWSWIRE) -- Global Oligonucleotide Synthesis Market to Cross USD 7 Billion by 2032 | DelveInsight The increasing occurrence of genetic disorders is a major ...

It completely quenches the fluorescence, while being capable of light-induced deprotection under UV-visible light irradiation, thereby restoring the fluorescence of the original fluorophore.

DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.biomac.4c01484. Reaction scheme for the solid-phase peptide synthesis ...

Shprintzen–Goldberg syndrome (SGS) is a multisystemic connective tissue disorder, with considerable clinical overlap with Marfan and Loeys–Dietz syndromes. These syndromes have commonly been ...

We determined that the tandem SH2 domain of S. cerevisiae Spt6 binds the linker region of the RNA polymerase II subunit Rpb1 rather than the expected sites in its heptad repeat domain. The 4 nM ...