In addition to the effect of IL-2 on flt3L-dependent DC development, IL-2 can also abrogate the ability of these DCs to stimulate T cells via an increase in DC apoptosis upon interaction with T cells.

Results: Six cell populations were mainly identified in the PCNSL tissue, including four types of immune cells—B cell, T cell, macrophage and dendritic cell—and two types of stromal cells: ...

A paradigm shift in the way we treat spinal injuries is now in sight, with the world's first regenerative cell therapy being granted approval for a registrational Phase I clinical trial.

Fuel cells powered with the metal could provide a new source of electric power that's far more energy-dense than lithium-ion batteries. A new type of fuel cell that runs on sodium metal could one ...

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of HNSCC, but many patients still exhibit poor responses due to insufficient T cell infiltration and impaired dendritic cell (DC) ...

Department of Laboratory Medicine, Experimental Cancer Medicine (ECM), Karolinska Institute, Center of Allogeneic Stem Cell Transplantation (CAST), Karolinska University Hospital Huddinge, 14186 ...

State Key Laboratory of Radiation Medicine and Protection, The Fourth Affiliated Hospital of Soochow University, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative ...

T regulatory cells, dendritic cells, macrophages, natural killer cells and neutrophils which are being developed as alternative immune cell therapies. NExT makes gene delivery quicker and less ...

“Immunotherapy has improved survival outcomes for patients with extensive-stage small cell lung cancer (ES-SCLC), marking meaningful progress in a historically challenging disease. However, despite ...

Oncolytic viruses trigger immunogenic cell death in tumors, releasing signals that activate innate immune cells and promote tumor-specific T-cell responses. While some oncolytic viruses, including FDA ...