Oncolytic viruses trigger immunogenic cell death in tumors, releasing signals that activate innate immune cells and promote tumor-specific T-cell responses. While some oncolytic viruses, including FDA ...

Proteogenomic analysis identified IFNγ as a driver of conventional dendritic cell type 2 maturation into migratory dendritic cells, which secreted cytokines Interleukin-12 and Interleukin-15.

Antigen-presenting cells (APCs) orchestrate T cell immunity. Retinoic acid receptor-related orphan receptor-γt (RORγt)-expressing APCs are heterogenous regulators of T cell tolerance but their ...

Dendritic cells (DC) are highly efficient antigen presenting cells being actively evaluated as vaccine components. A number of studies have shown adenovirus-mediated gene transfer to cultured DCs ...

Figure 2: T cell stimulatory capacity and morphology of CD40L-matured PDCs. Figure 3: Viability of DC subsets after stimulation with influenza and intracellular MxA expression. Figure 4 ...

T regulatory cells, dendritic cells, macrophages, natural killer cells and neutrophils which are being developed as alternative immune cell therapies. NExT makes gene delivery quicker and less ...

Dubodencel, also known as DOC1021, is a first-in-class, double-loaded autologous dendritic cell therapy that uniquely combines tumor lysate and amplified tumor-derived mRNA. The immunotherapy is ...

Fuel cells powered with the metal could provide a new source of electric power that's far more energy-dense than lithium-ion batteries. A new type of fuel cell that runs on sodium metal could one ...

In biology classes from high school through university, I learned that mitochondria are little objects that reside within each cell and serve as “powerhouses,” combining oxygen and food to ...

A paradigm shift in the way we treat spinal injuries is now in sight, with the world's first regenerative cell therapy being granted approval for a registrational Phase I clinical trial.