For my thesis project, I will interrogate drug effects on cell populations of the colon mucosa using single-nuclei RNA-sequencing (snRNA-seq) from DSS-colitis mice treated with or without SW033291 (a ...

Furthermore, when Axin1 ΔIEC and Axin1 ΔPC mice were cohoused with control mice, they became more susceptible to dextran sulfate sodium (DSS)-colitis, suggesting the protective role of Axin1 in ...

A dextran sodium sulfate (DSS)-induced colitis mouse model was constructed, and the animals were treated with MR-2938 (50 or 100 mg/kg).

Researchers from Chinese Academy of Sciences detailed the creation of a new dextran sulfate sodium (DSS)-based mouse model of immune checkpoint blockade (ICB) therapy-associated colitis. BioWorld ...

To their surprise, they found that the mice lacking DCIR showed reduced colitis severity and AOM-DSS-induced colorectal tumor growth. Moreover, compared to the wild-type mice (control), the DCIR ...

High- and low-dose dietary triclosan, in addition, caused worsening of colitis in a dextran sodium sulfate (DSS)-induced mouse model of inflammatory bowel disease (IBD). Exposure to triclosan was ...

It is estimated that more than 5 million people worldwide suffer from ulcerative colitis, a chronic inflammation of the colon that often progresses in stages whose causes have not yet been fully ...

In recent studies using the Dextran Sulfate Sodium (DSS) colitis mouse model, PALI-2108 demonstrated a dose-dependent effect on key fibrotic pathways, underscoring its potential as an effective ...