If you have ulcerative colitis (UC), you know that the physical symptoms—which include things like abdominal and rectal pain—can be challenging to deal with. However, the emotional side of ...

Here, we investigated the function of intestinal epithelial toll-like receptor (TLR) responses in the dextran sodium sulfate (DSS)-induced mouse model of colitis. Design We applied an in vivo genetic ...

Here, the role of the NLRP3 inflammasome in experimental colitis induced by dextran sodium sulfate (DSS) was examined. Results Macrophages incubated with DSS in vitro secreted high levels of IL-1β in ...

However, the exact mechanism is not yet fully understood. The pathological changes associated with dextran sodium sulfate (DSS)-induced colitis are similar to those in human UC. As a subgroup of the ...

The role of induced COPS8 was further demonstrated using intestinal specific COPS8 knockout (KO) mice, showing that MBELN‐mediated protection of mice from dextran sulfate sodium (DSS)‐induced colitis ...

Here, we analyze the roles of exosomes derived from M2a, M2b, and M2c macrophage phenotypes in dextran sulfate sodium (DSS)-induced colitis. Exosomes were isolated from the supernatant of different ...

Copyright: Published by Elsevier B.V. Ulcerative Colitis (UC) is an Inflammatory Bowel Disease (IBD) characterized by uncontrolled immune response, diarrhoea, weight ...

Here, we found chronic stress to sensitize mice to dextran sulfate sodium (DSS)-induced colitis; to increase the infiltration of B cells, neutrophils, and proinflammatory ly6C hi macrophages in ...

Dextran sodium sulfate (DSS) is a molecule that induces colitis like that seen in human patients. It is administered to the animal via their drinking water. This is a common model of Inflammatory ...