Whether you're getting started with PCR, sequencing, or diagnostics, tubes of custom DNA oligos will give you the exact, ...

Researchers at Tokyo University of Science have developed Chol-HDOs, which efficiently penetrate the brain, overcoming ...

Getting therapeutic drugs past the blood-brain barrier has long been a major challenge in treating brain diseases. Now, researchers have explored how cholesterol-modified heteroduplex oligonucleotides ...

Getting therapeutic drugs past the blood-brain barrier has long been one of medicine's most difficult challenges, limiting ...

We have developed an enhanced ratiometric fluorosensor using carbon dots (CDs) functionalized with Probe (single stranded complementary oligonucleotide fragment ... In both sensors, the presence of ...

DNA synthesis companies are largely separated by the length of DNA that they offer: short or long. Standard DNA oligos, synthesized through phosphoramidite synthesis—historically considered the ...

Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, ...

Here, we show that cyclin-dependent kinases (CDKs) regulate the phosphorylation of threonine 118 (T118) in PNKP. This phosphorylation allows recruitment to the gapped DNA structure found in ...

Since DNA-PAINT relies on stochastically blinking single molecules, identification of full protein structures or networks ... and at 309 nm for DBCO using a Nanodrop1000 spectrophotometer (Thermo ...

A joint team of professors—Hajun Kim, Taejoon Kwon, and Joo Hun Kang—from the Department of Biomedical Engineering at UNIST has unveiled a novel diagnostic technique that utilizes artificially ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Targeting Tyrosyl-DNA phosphodiesterase 1 ...