Precise replication of genetic material is essential to maintain genome stability. DNA replication is a tightly regulated process that ensues faithful copies of DNA molecules to daughter cells during ...

This study finds these bacteria as the first example of an organism using ADP-ribose modification of DNA as a mechanism for regulating gene transcription and cellular replication. The ...

the researchers discovered that PZL-A stabilizes the interaction between mutant POLγ variants and the DNA template during replication. Next, the investigators tested the effects of PZL-A on ...

POLG mutations impair mitochondrial DNA replication and cause diverse mitochondrial diseases. Here, the authors show that structural differences in the POLγB subunit between humans and mice ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. DNA i-motif structures are formed in the ...

Here, we combine a plasmonic nanoantenna with a solid-state nanopore and demonstrate that single DNA molecules can be efficiently delivered to the plasmonic hotspots and detected in a label-free ...

Ivy: Dull dull dull dull dull dull dull dull dull dull dull dull dull. Posey: No, you're not. Ivy: Not me! The flowers. I planted all these carnations months ago and I thought they'd be colourful ...