近期，哥本哈根大学诺和诺德基金会蛋白质研究中心的研究人员在npj Precision Oncology期刊上发表了一篇题为 “Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma” ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

We live in a golden age for space exploration. Scientists are gathering massive amounts of new information and scientific evidence at a record pace. Yet the age-old question remains unanswered: are w ...

Witness the fascinating world of DNA replication brought to life through magnetic ball experiments. These magnetic games use a unique visual approach to demonstrate how the building blocks of life ...

The PIF/Harbinger-derived ADF-IL protein recruits KAT2B to drive its nuclear translocation and local chromatin acetylation, ...

ATR 激酶是应对 DNA 复制应激（RS）的关键调节因子，在癌细胞中，许多遗传突变会导致 RS 水平升高，而 ATR 在维持复制叉的稳定性和促进细胞存活方面发挥着重要作用。抑制 ATR 可使癌细胞因复制叉崩溃和有丝分裂灾难而死亡，因此 ATR 成为癌症治疗的潜在靶点。目前，基于 ATR 抑制剂（ATRi）的临床试验正在开展，但尚未建立有效的治疗方案。

Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their ...

Announcing a new article publication for Zoonoses journal. Methicillin resistant Staphylococcus aureus (MRSA) and Vancomycin ...

Lucknow: The fusion of ancient Indian medicine and cutting-edge molecular biology promises to revolutionize healthcare.

Blacksmith Medicines, Inc. (Blacksmith), a leading biopharma dedicated to discovering and developing medicines targeting metalloenzymes, announced today that it will present preclinical data ...

DNA replication is happening continuously throughout the body, as many as trillions of times per day. Whenever a cell divides—whether to repair damaged tissue, replace old cells, or simply to help the ...