As the quest to extend human lifespan gains momentum, a select group of scientists is pioneering efforts to reverse the aging process. Inside state-of-the-art laboratories, researchers are ...

As time goes by, our bodies change, you know, even the brain. A major change is how brain structure seems to shrink with age. Studies show that this happens at both large and small levels inside. You ...

Experiments with tools designed to detect DNA damage reveal unique and conserved features of telomeres in cancer cells.

A new hereditary condition has been discovered that affects patients' ability to repair DNA—leaving them both at greater risk ...

Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival and homeostasis.

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired ...

Organisms have developed several DNA‐repair pathways as well as DNA‐damage checkpoints to cope with the frequent challenge of endogenous and exogenous DNA insults. In the absence or impairment of such ...

Survival is promoted through repair of these lesions by a number of DNA repair pathways. The efficacy of anticancer drugs is highly influenced by cellular DNA repair capacity. Inhibitors of DNA ...

DNA repair pathways are upregulated in tumors which can effectively process DNA damage caused by chemotherapy and radiation frequently used in cancer therapy. Increased chemo and radioresistance of ...