A home-built fiber optic surface plasmon resonance platform (FO-SPR) was applied to directly screen PCR amplified DNA for mutations. The FO-SPR sensor was used for real-time monitoring of DNA duplex ...

Nearest-neighbor thermodynamic (NNT) models currently provide some of the most accurate predictions of melting thermodynamics, including melting temperature (Tm) values, for short DNA duplexes.

As the size decreases, the melting temperature functions of pure metallic and bimetallic nanowires decrease almost with the same size-dependent trend. Due to the inclusion of the above effects, the ...