But James Watson and Francis Crick's claim was a valid one, for they had in fact discovered the structure of DNA, the chemical that encodes instructions for building and replicating almost all ...

Beyond the ladder-like structure described above, another key characteristic of double-stranded DNA is its unique three-dimensional shape. The first photographic evidence of this shape was ...

A recent study has identified a triple stranded HIV cDNA intermediate of reverse transcription, or a ‘central DNA flap,’ as a component of HIV nuclear import. The retroviral replication cycle ...

The pegRNA binds to a matching sequence on the target DNA strand. The Cas9 nickase cuts the unbound complementary strand, creating a flap. The dangling DNA flap binds to a matching sequence on the ...

So, once the pegRNA binds to the right part of the DNA, the Cas9 nickase cuts the strand and creates a DNA “flap.” The other end of the pegRNA acts as a template; part of it complements the flap, and ...

Blacksmith Medicines, Inc. (Blacksmith), a leading biopharma dedicated to discovering and developing medicines targeting metalloenzymes, announced today that it will present preclinical data ...