Cells are constantly subjected to DNA damage from a range of internal and environmental sources. It is estimated that cells ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

The G-loop acts like a landing pad for additional proteins. These proteins untie the G4 knot, break apart the G-loop and ...

Macquarie University researchers have discovered a naturally occurring protein found in human cells plays a powerful role in ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized ...

A new study in Nature Plants reveals that DNA double-strand break repair (DSBR) pathways help prevent gene transfer from organelles to the nucleus in plants. Disruption of DSBR increases the risk of ...

Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival and homeostasis.

Researchers at Northwestern University found that DNA strand separation may require more force than previously thought when modeled in a more true-to-life environment. In most labs, scientists ...

The interior of the cell is super crowded with molecules ... of fundamental biochemical processes. "If this affects DNA strand separation, all protein interactions with DNA are also going to ...

Delve into what the new CRISPR tool, CAST, has to offer. CRISPR-associated transposases are already gaining traction in ...

This first-in-the-world approach harnesses autophagy to shift DNA repair toward homologous recombination, boosting precision ...