Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

The G-loop acts like a landing pad for additional proteins. These proteins untie the G4 knot, break apart the G-loop and ...

The interior of the cell is super crowded with molecules ... of fundamental biochemical processes. "If this affects DNA strand separation, all protein interactions with DNA are also going to ...

Cells are constantly subjected to DNA damage from a range of internal and environmental sources. It is estimated that cells ...

Researchers at Northwestern University found that DNA strand separation may require more force than previously thought when modeled in a more true-to-life environment. In most labs, scientists ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such ...

Therefore, cells need tools to untie these knots quickly ... "With the help of proteins known for their role in DNA repair, RNA binds to the DNA strand opposite the G4 structure, forming a ...

Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival and homeostasis.

Delve into what the new CRISPR tool, CAST, has to offer. CRISPR-associated transposases are already gaining traction in ...

This first-in-the-world approach harnesses autophagy to shift DNA repair toward homologous recombination, boosting precision ...