Leveraging their unique structural attributes and facile modification capabilities, VLPs can serve as an effective platform for the delivery of tumor antigens, thereby stimulating the immune system ...
(2) These cells are activated using anti-CD3/CD28 antibodies to stimulate their proliferation. (3) Genetic modification of the T cells is performed by inserting the CAR gene, enabling them to ...
recognizes specific tumor antigens through its chimeric antigen receptor (CAR), leading to enhanced phagocytosis of the tumor cells and concomitant presentation of tumor antigen to T cells for their ...
State Key Laboratory of Pharmaceutical Biotechnology, Medical School of Nanjing University, Nanjing 210093, China Department of Andrology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical ...
Autoantibodies and tumor-associated antigens (TAAs) are increasingly recognized as valuable tools in the early detection and diagnosis of various cancers. Autoantibodies are immune proteins that ...
1Department of Pathology, Georgia Cancer Center at Augusta University, Augusta, Georgia.
High levels of the cancer antigen 15-3 (CA 15-3) can indicate that breast cancer is present or has spread to other parts of the body. Among other things, the CA 15-3 blood test can reflect how ...
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The TP53 gene or its proteins are also referred to as tumor protein TP53, cellular tumor antigen TP53, phosphoprotein TP53, antigen NY-CO-13, or transformation-related protein 53. Learn more below ...
The immune stimulatory effects of radiotherapy can be exploited by concurrent PI3Kγ inhibition to significantly constrain pancreatic cancer growth. Combined radiotherapy and PI3Kγ inhibition stimulate ...
primary focus on cancer vaccines. The shot is the lead product candidate from BioNTech's FixVac platform and is based on a combination of four mRNA-encoded, melanoma-associated antigens – NY-ESO ...