2019). The inflammatory cytokine IL-6 activates the Janus kinase (JAK) activation of signal transduction and transcription (STAT) signaling pathway, which inhibits expression of hepatocyte cytochrome ...

Find more information on the Altmetric Attention Score and how the score is calculated. Cytochrome P450 enzymes (P450s) are important in drug metabolism and have been linked to adverse drug reactions.

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Secondary forms of metabolic dysfunction-associated steatotic liver disease (MASLD) have different pathogeneses, ...

This review aims to provide a comprehensive perspective by contextualizing the historical and pharmacological significance of cannabinoids while focusing on their capacity to modulate the metabolic ...

Chronic kidney disease (CKD) represents a global health issue with a high socioeconomic impact. Beyond a progressive decline of kidney function, patients with CKD are at increased risk of ...

Contributed by Rafael Radi; received August 8, 2022; accepted October 13, 2022; reviewed by Miguel De la Rosa and Mark Mamula ...

In this study, the protocol for liver cytochrome P450 (CYP) analysis from the native Brazilian fish Ancistrus multispinis was established. The microsome contamination by hemoglobin during the analysis ...