Sister chromatid cohesion, which is essential for mitosis, is mediated by a multi-subunit protein complex called cohesin. Cohesin’s Scc1, Smc1 and Smc3 subunits form a tripartite ring structure ...

Twenty years ago, the protein complex cohesin was first described by researchers. They found that its shape strikingly corresponds to its function: when a cell divides, the ring-shaped structure ...

The study, "Opening of cohesin's SMC ring is essential for timely DNA replication and DNA loop formation," was published in the journal Cell Reports on April 27, 2021 at https: ...

The ring-shaped cohesin complex ensures that each round of cell division yields two daughter cells with identical sets of chromosomes. The peculiar molecule and its function were discovered in Kim ...

Best known for its ability to regulate the separation of sister chromatids during cell division, the cohesin protein complex, a ring-shaped structure, has shown that it has other powers, such as ...

They found that its shape strikingly corresponds to its function: when a cell divides, the ring-shaped structure of cohesin keeps sister-chromatids tied together until they are ready to separate.

Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA and creates specific loops in the genetic material which determine the ...

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Cohesin is a ring-shaped protein complex involved in the spatial organization of the genome and in mitotic chromosome structure. Vertebrate somatic cells have two versions of cohesin that contain ...

Massive sequencing of cancer genomes brings to light new genes every day that could be involved in the process of tumour formation. A good example of this is cohesin, a ring-shaped protein complex ...

A diagram of the protein complex cohesin in its assumed ring-shaped configuration. The scissors represent the action of the enzyme Cut1, which breaks apart the molecule to release DNA.