Cocaine, a drug of abuse, activates just a portion—10% to 20%—of the neurons in the brain's nucleus accumbens, a critical ...

Cocaine, a drug of abuse, activates just a portion - 10 to 20 percent - of the neurons in the brain's nucleus accumbens, a ...

The VTA is also one of several areas where the neurotransmitter occurs naturally. In their experiments, the researchers observed increased locomotor activity, comparable to that seen with cocaine ...

(Jan. 10, 2019) --Researchers at UTSA have revealed significant insight into cocaine addiction, a phenomenon which has grown significantly in the United States since 2015. Now new data by UTSA shows ...

Drugs of abuse abet, or interfere with the chemical messengers, or neurotransmitters. The neurotransmitters that facilitate addiction are released by the 10 billion neurons that deal with ...

Dopamine also explains why the use of drugs such as cocaine produces pleasure by blocking the absorption of the ...

Drugs that bind to neurotransmitter receptors, mimicking the activity of a neurotransmitter chemical binding to the receptor, are called agonists, per the Merck Manual. Antagonist drugs block a ...

Once packaged with their neurotransmitter cargo the vesicles ... “This transporter is a target for pharmacologically relevant drugs used in the treatment of hyperkinetic disorders such as ...

The neurotransmitter transporters have also proved to be very important targets for CNS drug discovery, particularly for antidepressant drugs. Virtually all of the modern generation of ...